Pharmaceutical blending is a documentation exercise with a mechanical component. Contamination control, cleanability and process validation decide whether a machine can be installed at all; capacity and cycle time come after.
Our pharma configurations are built around that order: mirror-polished 316L, crevice-free welds, full discharge, CIP/SIP provisions and a documentation package covering material certificates and installation and operational qualification. Double cone and V-shape machines handle API and excipient blending; plough machines cover wet granulation.
GMP-ready design features
Documentation
Installation and operational qualification packages, material certificates for contact parts and a documented build sequence for regulatory submission.
Surface finish
Mirror-polished SS316L around Ra 0.4 µm, passivated and free of crevices, so cleaning validation has a surface it can defend.
CIP / WIP provisions
Spray balls, self-draining geometry and quick-release shaft seals, with manual access where the product requires it.
Batch records
PLC options with audit trail, electronic signatures and batch parameter recording for 21 CFR Part 11 environments.
Pharma and nutraceutical applications
API blending
Uniform distribution of active ingredients into excipients in double cone and V-shape machines, with sampling ports for validation.
Wet and dry granulation
Plough shear mixing with choppers for dense, uniform granules ahead of tableting or capsule filling.
Excipient pre-mixing
Fillers, binders, disintegrants and lubricants blended in larger volumes before the active is introduced.
Nutraceuticals and supplements
Protein, vitamin, mineral and herbal extract blends in GMP-grade machines at 50–1,000 L.
Pharma-grade equipment
Double Cone Mixer (DCM)
The standard pharmaceutical blender: mirror-polished 316L, CIP-compatible, with IQ/OQ documentation.
View specifications → GranulationPlough Shear Mixer (LDH)
High-shear wet granulation with optional vacuum drying, multi-chopper and liquid injection.
View specifications → Lab and clinicalV Powder Mixer (V Series)
5–1,000 L for R&D, pilot and clinical trial material — the same finish and documentation as production.
View specifications → Dust controlVacuum Conveyor (VC)
Enclosed transfer from blender to tablet press or capsule filler, with HEPA-filtered exhaust.
View specifications →Read next
Frequently asked questions
Are the machines GMP compliant?
The V-shape and double cone configurations are built to GMP expectations: mirror-polished 316L, sanitary welds, no crevices, full discharge, with IQ/OQ documentation. Final compliance is established by your cleaning and process validation.
Can you supply material certificates?
Yes — 3.1 certificates for contact parts, plus a documentation package for facilities under FDA or MHRA audit.
What is the smallest batch?
A 5 L V-shape machine handles development batches; production units run to 1,500 L on the double cone and 4,000 L on the plough. Uniformity is validated per product, not assumed from the model number.
Need pharmaceutical equipment?
Tell us the material, batch size and any compliance or containment requirement. We will come back with the configuration we would build and the questions we would ask before quoting.
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